The methylation pathway is a complex biochemical process that occurs in every cell of the human body. It involves the addition of a methyl group (CH3) to various molecules, including DNA, RNA, and proteins, which can impact gene expression and cellular function. It is also closely tied to our mental health and neurological regulation, therefore having an impact on a number of factors throughout the body. Optimising methylation is key to both health in both optimisation but also disease prevention.
Several genes are involved in the methylation pathway, including MTHFR, MTR, and MTRR. These genes code for enzymes that are essential for proper methylation. However, the methylation pathway can also be influenced by external factors such as diet, inflammation, and stress.
For example, certain nutrients such as folate, vitamin B12, and choline are important for proper methylation. Inflammation can disrupt the methylation process by altering gene expression and enzyme activity. Chronic stress can also impact methylation by altering gene expression and reducing the availability of key nutrients.
At The Nadura Clinic, various testing methods including DNA genetic SNPs panels, FEBS blood testing & Dutch Complete may be used to assess an individual’s methylation status and identify any imbalances or deficiencies that may be contributing to health issues. These testing methods may include genetic testing to evaluate gene variants associated with methylation, blood tests to measure nutrient levels, and functional testing to assess the impact of stress and inflammation on methylation. Based on the results of these tests, personalized treatment plans can be developed to support optimal methylation and overall health.
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