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Clinical lab results H-Pylori & antibiotic resistance – The Nadura Clinic

This is an insight into our functional testing and lab analysis at The Nadura Clinic, and an example of some of the results we get through nutritional intervention, laboratory analysis and lifestyle medicine.

The digestive system

Over eighty percent of our clients presenting across our clinics attend with digestive issues. These issues range from acute to chronic or even severe but are all are commonly characterized as “a poor stomach” by the client. Many have previously exhausted multiple different therapy’s and attended many different clinics, and all too often are truly not expecting results.

Test don’t guess

While we complete many laboratory tests at the clinic the skill is to arrive at the right test that will uncover the root cause of the presenting symptom. A re-test will allow for actual measurable results, firstly to see if the issue has been eradicated and secondly to see if this has improved symptoms.

One of these tests that proves very beneficial is GI MAP.

Let’s look at a case study on one of our recent tests

Clinical lab results for positive H-Pylori & antibiotic resistance. Let’s take a closer look at H- pylori antibiotic resistance, together with initial investigation and the subsequent follow up results from a GI map (Stool analysis) completed at out clinic in 2020 through DX solutions lab at Nordic laboratories.

A female in her late twenties presented with chronic inflammatory stomach issues including constant hunger pains, pains between meals, reflux, heartburn, constant bloating, acne and annoying pain in her abdomen. She had been treated on three separate occasions by her GP for H pylori but each treatment at failed to either remove the bacterium or improve the symptoms. She was subsequently referred by her GP for further gastro investigation to our team at The Nadura Clinic.

H-pylori is gram negative bacteria that causes chronic inflammation mainly via its outer membrane known as LPS. Over 80% of gastric ulcers are caused by H pylori, which is involved in the pathogenesis of gastric cancer and a unique lymphoma involving the gut mucosa (mucosal associated lymphatic tissue lymphoma). Other symptoms linked to H- pylori include skin rashes like urticaria, chronic joint pain, some autoimmune diseases and eye inflammation. It affects up to 70% of the population and is becoming more and more prominent.

A major factor is prior, poor stomach acid secretion usually from chronic PPI usage as well as poor cofactors status zinc, B6, magnesium & thiamine and chronic stress affecting vagal nerve tone.

Gastro symptoms include;

  • Bloating
  • Skin eruptions
  • Excess wind
  • Gnawing pain (particularly between meals)
  • Heartburn
  • Reflux
  • Pain
  • Fatigue
  • Bad breath

Depending on the duration of the infection virulence factors which we also test for, are important as they can predispose to specific pathogenic pathways.

This particular lady had had exhausted all conventional treatment.

We started a DNA stool analysis to get a grasp of her overall microbiome health, and not just H pylori (Treat the person and not the test) as you can see from her retest  below we have managed to greatly reduce her level of H pylori over the ten weeks which has made substantial improvement to her presenting symptoms.

By using a professional therapeutic alliance with the lab, accurate lab testing (and being able to accurately interpret it) combined with an individualised and targeted plan of both dietary and nutraceutical intervention, we can evidently have a profound effect on this bacterial resistance within the bowl itself.

More about GI Map at The Nadura Clinic

GI Map (Microbial Assay Plus) – The absolute gold standard in digestive analysis. GI Map is an unparalleled DNA based stool analysis delivering innovative, accurate and clinically relevant diagnostic testing in the lab with full detailed interpretation from our internal nurse and nutritionist here at The Nadura Clinic

The Gastrointestinal Microbial Assay Plus (GI-MAP®) is an innovative clinical tool that measures gastrointestinal microbiota DNA from a single stool sample with state of the art, quantitative polymerase chain reaction (qPCR or real-time PCR) technology.

The GI-MAP was designed to detect microbes that may be disturbing normal microbial balance or contributing to illness as well as indicators

of digestion, absorption, inflammation, and immune function. The following guide may be useful for understanding the nature of each of the microorganisms found on the GI-MAP, as well as clinical implications and treatment guidelines.

Contact the clinic

The Nadura Clinic has a national presence with full time clinics in Kelly’s Pharmacy Dungarvan, at the Roche Clinic in Kilkenny, Vista Primary Care, Clinic Naas, also a number of satellite clinics complemented by their virtual clinic to serve international clients. The clinic also run the nutrition and functional testing at the exclusive 5 star Ros Glas recovery clinic here in Ireland which is one of the leading private clinics in the globe.

Call Lisa Tobin-Leech our clinic manager on 087 3492991or email you query to hello@nadura.ie